Dysplastic Gangliocytoma: A Rare Example of Cerebellar Tumor with An Evident Genetic Profile (Cowden Syndrome)
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چکیده
منابع مشابه
Lhermitte-Duclos Disease (Dysplastic Cerebellar Gangliocytoma) in a Young Patient
Lhermitte Duclos disease also called dysplastic gangliocytoma of cerebellum is an extremely rare cerebellar neoplasm. It usually presents with raised intracranial pressure along with cerebellar signs. We report a rare case of Lhermitte Duclos disease of a 20 years male who presented with signs & symptoms of raised intracranial tension. CT features were suggestive of Lhermitte-Duclos disease. Su...
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Do the results from Paoletti et al. (6) justify PFS as an endpoint for trials of advanced gastric cancer? The authors conclude that the answer is no, but it is not entirely clear how they reached this conclusion. They quote a number of statistics that characterize in various ways the concordance of PFS and OS results, in addition to R 2. However, these measures are all ultimately descriptive an...
متن کاملAcute Hydrocephalus Revealing Unusual Cerebellar Mass: Dysplastic Cerebellar Gangliocytoma or Lhermitte-Duclos Disease (LDD)
Lhermitte-Duclos disease (LDD) or dysplastic gangliocytoma of the cerebellum is a rare benign lesion of uncertain pathogenesis characterized by overgrowth of cerebellar ganglion cells which replace granular cells and Purkinje cells; this results in gross thickening of the cerebellar folia. It is revealed by symptoms of raised intracranial pressure, cerebellar impairment and obstructive hydrocep...
متن کاملAssessing a Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) with 7T MR Imaging
Lhermitte-Duclos disease (LDD; dysplastic cerebellar gangliocytoma) is a rare hamartomatous lesion of the cerebellar cortex and this was first described in 1920. LDD is considered to be part of the autosomal-dominant phacomatosis and cancer syndrome Cowden disease (CS). We examined the brain of a 46-year-old man, who displayed the manifestations of CS, with 7 Tesla (T) and 1.5 T MRI and 1.5 T M...
متن کاملLhermitte - duclos Disease :
Lhermitte-Duclos disease (LDD) is a benign neoplasm of posterior fossa, involving cerebellum. It is also known as dysplastic cerebellar gangliocytoma. It is not a true neoplasm but a hamartoma. It can be either isolated finding or associated with Cowden (multiple hamartoma syndrome). adults.
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ژورنال
عنوان ژورنال: Open Journal of Pathology
سال: 2021
ISSN: 2164-6775,2164-6783
DOI: 10.4236/ojpathology.2021.112004